Three points to bear in mind when considering an event in the Czech Republic:
Prague/the Czech Republic is an aspirational destination which will appeal to all visitors including those attending the event and accompanying persons. It is not a hard sell.
Given its geographical location and its excellent accessibility Prague is a superb cost effective and time effective destination. You can operate a two day programme with delegates coming from most of Europe and just need to spend one night in Prague. However we would prefer you to stay longer!!
Prague is a great walking city and many events can be undertaken by just taking a leisurely stroll or a short transfer to the venue.